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The Science Behind Intermittent Fasting

In the world of weight loss strategies, intermittent fasting has gained significant attention for its effectiveness and potential health benefits. But what exactly is intermittent fasting, and how does it work? In this blog post, we'll delve into the science behind intermittent fasting, exploring its impact on metabolism and weight loss. By understanding the underlying mechanisms, you can make an informed decision about whether intermittent fasting is the right approach for you.

Understanding Metabolism and Weight Loss

Before diving into the specifics of intermittent fasting, let's first understand the role of metabolism in weight loss. Your metabolism refers to the chemical processes that occur within your body to convert food into energy. It involves two key components:

  1. Basal Metabolic Rate (BMR): This represents the energy your body needs to perform basic functions such as breathing, circulating blood, and maintaining organ function. BMR accounts for the majority of the calories you burn throughout the day.
  2. Thermic Effect of Food (TEF): This refers to the energy required for digestion, absorption, and utilization of nutrients from the food you consume. Different macronutrients have varying effects on TEF, with protein requiring more energy to digest compared to fats and carbohydrates.

Intermittent Fasting and Weight Loss

Weight loss occurs when you create a calorie deficit, meaning you consume fewer calories than your body requires. This deficit prompts your body to tap into its energy stores, including fat, to meet its energy needs. Various factors, including age, sex, body composition, and activity level, influence your metabolic rate and the rate at which you burn calories.

Intermittent fasting is an eating pattern that cycles between periods of fasting and eating. The most popular methods include:

  1. 16/8 Method: This involves fasting for 16 hours and restricting your eating window to 8 hours each day.
  2. 5:2 Diet: With this approach, you consume a normal diet for five days of the week and restrict calorie intake to 500-600 calories for two non-consecutive days.
  3. Alternate-Day Fasting: This method involves fasting every other day or significantly reducing calorie intake on fasting days.

Intermittent fasting promotes weight loss through several mechanisms:

  1. Calorie Restriction: By limiting the time window for eating, you naturally reduce your overall calorie intake. This can create a calorie deficit, leading to weight loss over time.
  2. Insulin Regulation: Fasting periods help regulate insulin levels in the body. Lower insulin levels facilitate fat burning by allowing stored fat to be released and utilized for energy.
  3. Increased Fat Oxidation: During fasting, your body shifts from using glucose as its primary fuel source to burning stored fat. This increased fat oxidation can contribute to weight loss, particularly in the abdominal area.
  4. Enhanced Autophagy: Intermittent fasting stimulates autophagy, a cellular process that removes damaged cells and promotes cellular regeneration. This may have beneficial effects on overall health and metabolism.
  5. Hormonal Changes: Fasting can affect hormone levels, including an increase in human growth hormone (HGH). HGH aids in fat metabolism and muscle growth, contributing to improved body composition.


Intermittent fasting has gained popularity for its potential benefits in weight loss and overall health. The Physician's Plan team of medical providers, and weight loss counselors design your Intermittent Fasting plan to ensure maximum results and fit your lifestyle. Delay, don't deny. We'll teach you how.


Call a center near you, use our chat room, or book an appointment online. Lose weight. Plan on it.